Joseph Elich
Director, mRNA Process Development Prime Medicine
Seminars
Thursday 1st October 2026
Panel Discussion: Accelerating mRNA CGT Therapies: Balancing Phase-Appropriate Quality & CMC Complexity
2:30 pm
- How are emerging mRNA modalities in CGT changing the biggest process development and CMC challenges teams need to solve today?
- Where are current analytical and control strategies falling short when applied across diverse mRNA-enabled CGT applications – and how should they evolve?
- What does a truly scalable and flexible CMC framework look like when supporting multiple mRNA-driven CGT modalities with differing requirements?
Thursday 1st October 2026
Applying a Scalable mRNA Process Platform for Ex-Vivo & In-Vivo Gene Editing
3:00 pm
- Exploring key CMC and process development considerations for delivering RNAbased gene editing systems across in vivo (e.g. LNP) and ex vivo manufacturing workflows
- Addressing challenges in achieving consistent editing efficiency while maintaining product quality, potency, and safety across different delivery modalities and target tissues
- Discussing how platform-based development strategies can support scalability, tech transfer, and clinical translation of next-generation genetic medicines
