About the 5th mRNA Process Development & CMC Summit

Key questions include:

• How are teams successfully translating high-throughput, discovery-stage LNP workflows into robust, GMP-ready processes without compromising product quality?
• Where do current LNP workflows break when moving from preclinical into clinical and commercial scale – and how can these gaps be addressed early?
• What needs to change today to ensure LNP platforms remain scalable, reproducible, and cost-effective as products move toward global commercial supply?

• Developing scalable, semi-automated workflows to streamline mRNA and LNP production from plasmid DNA through to encapsulated product for rapid preclinical evaluation
• Leveraging liquid handling systems and high-throughput screening platforms to accelerate formulation optimization while maintaining material quality suitable for in vivo studies
• Sharing lessons learned from translating mRNA and LNP processes across bench-scale, GMP manufacturing, and miniaturized automated screening systems