Leveraging NGS to Enable Scalable QC & Process Control for Complex Multivariant mRNA Vaccines

  • Exploring how NGS can consolidate multiple critical quality attributes into a single, data-rich analytical workflow for complex mRNA products
  • Overcoming the QC and CMC challenges associated with 22-component multivariant RNA vaccines where traditional analytical methods struggle to assess integrity, identity & potency at scale
  • Sharing lessons learned from implementing next-generation sequencing approaches for in-process control, release testing & regulatory readiness in next-generation mRNA vaccine development