Leveraging High-Throughput Automation & Analytical Development to Accelerate Cross-Modality mRNA & circRNA Process Optimization
- Exploring lessons learned transitioning process development strategies from self-amplifying RNA to circRNA platforms, including upstream IVT optimization,circularization workflows, and downstream purification considerations
- Demonstrating how automated high-throughput experimentation can accelerate reaction chemistry optimization, analytical assay development, and impurity characterization across emerging RNA constructs
- Discussing approaches to building adaptable, cross-functional manufacturing and analytical frameworks capable of supporting the growing complexity of nextgeneration RNA therapeutics and advanced therapy applications